One of the best ways you can practice self-care? PrEP, a medication that can reduce your risk of getting HIV.

Get the information you need and find out if PrEP is right for you.

What does PrEP stand for?

Short for pre-exposure prophylaxis (that’s a mouthful), PrEP is used by HIV-negative people to remain HIV-negative.

Does PrEP work?

Yes! When used as directed, PrEP is highly effective at preventing HIV.

How do you take PrEP?

When it comes to taking PrEP, there’s good news: you have options. There are two ways you can add PrEP into your self-care routine.

• Daily pill: There are two pills available under the trademarks Truvada® and Descovy®. There are also generic versions of Truvada® available in the United States. These pills are taken daily.
• Injectable: You may have heard of Apretude, another name for injectable PrEP, which is given every other month—or six times per year. To make sure it’s administered properly, it’s given by a healthcare provider.

Who uses PrEP?

If you don’t have HIV, PrEP could be for you. It helps HIV-negative people stay negative, and can be an especially helpful tool for:

• People who have sex with more than one partner and may not know their HIV status
• Anyone in a sexual relationship with someone who is HIV-positive and has an unknown or detectable viral load
• People who inject drugs, especially if they share needles, syringes, and/or other drug injection equipment
• People who have been prescribed PEP, including people who have been prescribed PEP multiple times—learn more about PEP.

Is PrEP right for me?

Only you can answer this question! Whether or not PrEP works for your self-care routine is up to you.  You may want to consider PrEP if you:

• have a difficult time accessing or using condoms regularly, or you don’t use condoms during sex
• inject drugs and share needles, syringes, and/or other drug injection equipment with someone who is HIV-positive, or whose HIV status you do not know
• want to add an extra layer of protection against HIV on top of other precautions you are already taking
• have been diagnosed with an STD/STI in the past 6 months

Take a short quiz to learn if PrEP may be right for you.

Does PrEP prevent other STDs/STIs or viral hepatitis?

PrEP is very effective at preventing HIV when used as prescribed, but it does NOT prevent other STDs/STIs, viral hepatitis, or pregnancy. That’s why PrEP shouldn’t be the only part of your self-care and sexual health routines.

Always use condoms when you’re having sex and always use new needles, syringes, and/or other drug injection equipment like cottons and cookers if you’re injecting drugs.

What’s the difference between PrEP and PEP?

The names are so similar—it can be confusing! But while PrEP and PEP both help prevent HIV, they are very different.

While PrEP is taken to prevent HIV, PEP, sometimes called nPEP, stands for post-exposure prophylaxis and should be taken after an event that may have exposed you to HIV. It’s a four-week course of medication that should be started as soon as possible after exposure, ideally within a few hours, but no later than 72 hours, after exposure.

How can I get a prescription for PrEP?

If you’ve decided PrEP could be right for you, the first step to getting a prescription is to talk with a healthcare provider.

Not sure where to find one? Check out the services map to find a PrEP provider near you.

Once you have the conversation and you’re confirmed to be HIV-negative, you can get a prescription for the kind of PrEP that works for you. Your doctor you continue to be tested for HIV and STDs/STIs, just to make sure PrEP continues to be a healthy part of your routine.

Is PrEP covered by insurance?

If you have health insurance, the cost of PrEP is usually covered with no out-of-pocket costs.

If you don’t have insurance, or need help with your co-pays, the Massachusetts PrEP Drug Assistance Program (PrEPDAP) may be able to help cover the cost. PrEPDAP also assists eligible clients by covering out-of-pocket costs for PrEP, such as co-pays and payments towards an insurance deductible. Learn more about paying for PrEP.

What else can I do to prevent HIV?

Whether or not you take PrEP, here are a few other ways to reduce the chances of getting HIV:

• Get tested every 3-6 months for HIV/STDs/STIs and complete any necessary treatment as prescribed. Find a testing location near you.
• Talk with your sex partners about their STD/STI testing history and their HIV status.
• If your sex partners are HIV-positive, talk with them about their current HIV treatments, and have sex only when they have an undetectable viral load, which is when a viral load is so low that it cannot be detected by tests.
• If you inject drugs, make sure to use new needles, syringes, and/or other injection equipment to reduce your risk.
• Enjoy sex that has a lower chance of transmitting HIV, such as oral sex, mutual masturbation, etc.
• Use condoms for anal and/or vaginal sex.
• Use plenty of water-based lubricants to help reduce friction and tearing during sex.